
任吉存
任吉存,男 ,上海交通大学化学化工学院教授。1994年于武汉大学获得分析化学专业博士学位。1994年7 月-1996年3 月任湖南师範大学化学系副教授,系副主任,并在湖南医科大学从事博士后工作。1996 年3 月至2000 年3月在挪威Bergen大学参加欧共体重大基金项目研究。1997年晋升教授。2001年起任上海交通大学化学化工学院教授,博士生导师。
基本介绍
- 中文名:任吉存
- 毕业院校:武汉大学
- 学位/学历:博士
- 专业方向:单分子(单颗粒)波动光谱与成像、光学探针设计与合成
人物经历
1978-1981:安庆师範学院化学系,学士
1991-1994:武汉大学化学学院,博士
1994-1996:中南大学湘雅医学院,博士后
1996-2000:挪威卑尔根大学医学院,博士后
1991-1994:武汉大学化学学院,博士
1994-1996:中南大学湘雅医学院,博士后
1996-2000:挪威卑尔根大学医学院,博士后
1982-1991:安庆师範学院化学系,助教,讲师
1994-1996:湖南师範大学化学系,副教授
1997-2001:湖南师範大学化学系,教授
2001-2015:上海交通大学化学化工学院,教授
1994-1996:湖南师範大学化学系,副教授
1997-2001:湖南师範大学化学系,教授
2001-2015:上海交通大学化学化工学院,教授
2015 - 上海交通大学,特聘教授
研究方向
1)单分子(单颗粒)波动光谱与成像: 发展单分子(单颗粒)波动光谱与成像新方法,与微流控晶片技术结合,研究活细胞内生物分子、药物分子的动力学以及分子间(药物分子与靶标、蛋白-蛋白)的相互作用。
(2)光学探针设计与合成:设计合成新型的纳米光学探针和萤光分子探针,发展活细胞内生物分子的标记新方法。
(3)生物分析:基于微流控晶片电泳和纳米光学探针标记技术,发展高灵敏度的分析新方法,用于疾病标誌物、环境污染物分析。
科研项目
主持国家自然科学基金重点项目、科学仪器基础研究项目、面上项目,科技部“863”专项,上海科委重点项目等。参与 “973”计画项目,国家自然科学基金重点项目,上海市专项等项目。
荣誉奖励
2016年获教育部自然科学一等奖
2015年上海交通大学特聘教授
2008年获教育部自然科学二等奖
学术兼职
Electrophoresis (Wiley), Microchimica Acta (Springer), Journal of Separation Science (Wiley), Methods and Applications inFluorescence (IOP),《分析化学》,《色谱》等杂誌编委, 国际萤光光谱学方法和套用大会(Methods and Applications inFluorescence, MAF)督导委员会委员(Permanent Steering Committee )
教学工作
本科生:《仪器分析》
研究生:《现代仪器分析》
研究生:《现代仪器分析》
发布论文
Zhixue Du, Jing Yu,Fucai Li,Liyun Deng, Fang Wu, Xiangyi Huang, Jan Bergstrand, Jerker Widengren, Chaoqing Dong* and Jicun Ren* In situ monitoring p53 protein and MDM2 protein interaction in single living cells using single molecule fluorescence spectroscopy, Anal. Chem., 2018, 90, 6144−6151.
Lvping Cai, Liyun Deng, Xiangyi Huang*, Jicun Ren*, Catalytic Chemiluminescence Polymer Dots for Ultrasensitive In Vivo Imaging of Intrinsic Reactive Oxygen Species in Mice, Anal. Chem., 2018, 90, 6929−6935.
Di Su, Chaoqing Dong and Jicun Ren* Quantitative Determination of Telomerase Activity by Combining Fluorescence Correlation Spectroscopy with Telomerase Repeat Amplification Protocol, Anal. Chem., 2018,90, 10006-1013.
Fang Yi, Xiangyi Huang, Jicun Ren, Simple and Sensitive Method for Determination of Protein Kinase Activity Based on Surface Charge Change of Peptide-Modified Gold Nanoparticles As Substrates, Anal. Chem., 2018, 90, 3871−3877.
Bocheng Zhang, Chaoqing Dong and Jicun Ren* Size Distribution of Noble Metal Nanoparticles Characterized by Combing Resonance Light Scattering Correlation Spectroscopy with Maximum Entropy Method ,Anal. Chem., 2017, 89(22), 12609–12616.
Di Su, Chaoqing Dong, and Jicun Ren* Determination of caspase-3 activity and its inhibition constant by combination of fluorescence correlation spectroscopy with a microwell chip,
Anal. Chem., 2017, 89, 9788−9796.
Jinjie Wang, Chaoqing Dong, Jicun Ren* Fluorescence and scattering light cross correlation spectroscopy and its applications in homogeneous immunoassay,Anal. Chem., 2017,89, 5230−5237.
Aidi Zhang, Chaoqing Dong*, and Jicun Ren* Tuning Blinking Behavior of Highly Luminescent Cesium Lead Halide Nanocrystals through Fast Anion-Exchange Reactions, J. Phys. Chem. C, 2017, 121, 13314−13323.
Heng Liu, Chaoqing Dong, Jicun Ren*, Tempo-Spatially Resolved Scattering Correlation Spectroscopy Based on Dark-Field Microscopy and Its Application to Investigate Dynamic Behaviors of Gold Nanoparticles in Live Cells,
J. Am. Chem. Soc., 2014, 136, 2775−2785.
Chaoqing Dong, Heng Liu, Aidi Zhang, Jicun RenControllable Blinking-to-Nonblinking Behavior of Aqueous CdTeS Alloyed Quantum Dots, Chem. Eur. J.2014, 20(7): 1940-1946.
Chaoqing Dong, Heng Liu, Jicun Ren Assessing the blinking state of fluorescent quantum dots in free solution by combining fluorescence correlation spectroscopy with ensemble spectroscopic methods, Langmuir,2014, 30, 12969−12976.
Aidi Zhang, Chaoqing Dong, Heng Liu and Jicun Ren*, Blinking Behavior of CdSe/CdS Quantum Dots Controlled by Alkylthiols as Surface Trap Modifiers, J. Phys. Chem. C, 2013, 117, 24592−24600.
Bocheng Zhang, Tao Lan, Xiangyi Huang, Chaoqing Dong and Jicun Ren*, Sensitive Single Particle Method for Characterizing Rapid Rotational and Translational Diffusion and Aspect Ratio of Anisotropic Nanoparticles and Its Application in Immunoassays Anal. Chem., 2013, 85, 9433−9438.
Xiangyi Huang, Jicun Ren*, Nanoparticle-Based Chemiluminescence Resonance Energy Transfer: A strategy to develop new analytical methods, TrAC:Trends in Analytical Chemistry, 2012, 40, 77-89.
Lingao Ruan, Zhancheng Xu, Tao Lan, Jinjie Wang, Heng Liu, Chaodong Li Chaoqing Dong, Jicun Ren*, Highly Sensitive Method for Assay of Drug-induced Apoptosis Using Fluorescence Correlation Spectroscopy, Anal. Chem., 2012, 84, 7350−7358.
Heng Liu, Chaoqing Dong, Xiangyi Huang, Jicun Ren*, Spatially Resolved Scattering Correlation Spectroscopy Using A Total Internal Reflection (TIR) Configuration , Anal. Chem., 2012, 84, 3561−3567.
Jie Gao, Xiangyi Huang, Heng Liu, Feng Zan, Jicun Ren *, Colloidal stability of gold nanoparticles modified with thiol compounds, bioconjugation and application in cancer cell imaging, Langmuir, 2012, 28, 4464-4471.
Feng Zan, Chaoqing Dong, Heng Liu, Jicun Ren* Experimental studies on blinking behavior of single InP/ZnS quantum dots: Effects of synthetic conditions and UV irradiation, J. Phys. Chem. C, 2012, 116, 3944−3950.
Feng Zan, Jicun Ren* Gas-liquid phase synthesis of highly luminescent InP/ZnS core/shell quantum dots using zinc phosphide as a new phosphorus source, J. Mater. Chem., 2012, 22, 1794-1799.
Hua He, Chao Xie, Jicun Ren*, Non-Bleaching Fluorescence of Gold Nanoparticles and Its Applications in Cancer Cell Imaging, Anal. Chem., 2008, 80, 5951-5957.
Chaoqing Dong, Jiacheng Guo, Liwen Shao, Jicun Ren* Host-guest interaction of chaperonin GroEL and water soluble CdTe QDs and its size selective encapsulation, ChemPhysChem., 2008, 9, 2245-2251.
Huifeng Qian, Chaoqing Dong, Jinliang Peng, Xin Qiu, Yuhong Xu, Jicun Ren*, High Quality and Water-Soluble Near-Infrared Photoluminescent CdHgTe/CdS Quantum Dots Prepared by Adjusting Size and Composition,J. Phys. Chem. C., 2007, 111, 16852-16857.
Kanglin Wang, Xin Qiu, Chaoqing Dong, Jicun Ren*, Single molecule technology for rapid detection of DNA hybridization based on resonance light scattering of gold nanoparticles as probes, ChemBioChem., 2007, 8, 1126-1129.
Chaoqing Dong, Jicun Ren*, On-line investigation of laser-induced aggregation and photo-activation of CdTe quantum dots by fluorescence correlation spectroscopy,J. Phys. Chem. C, 2007, 111, 7918-7923.
Hua He, Huifeng Qian, Chaoqing Dong, Kanglin Wang,Jicun Ren*, Single Nonblinking CdTe Quantum Dots Synthesized in Aqueous Thiopropionic Acid,Angew. Chem. Int. Ed. 2006, 45, 7588-7591.
Xiangyi Huang, Liang Li, Huifeng Qian, Chaoqing Dong, Jicun Ren* A Resonance Energy Transfer between Chemiluminescence Donors and CdTe Quantum Dots Acceptors (CRET), Angew. Chem. Int. Ed., 2006, 45, 5140-5143.
Chaoqing Dong, Huifeng Qian, Nenghu Fang and Jicun Ren*, Study of Fluorescence Quenching and Dialysis Process of CdTe Quantum Dot Using Ensemble Techniques and Fluorescence Correlation Spectroscopy, J. Phys. Chem. B, 2006, 110,11069-11075.
Huifeng Qian, Xing Qiu, Liang Li, Jicun Ren* Microwave assisted aqueous synthesis: a rapid approach to prepare highly luminescent ZnSe(S) alloyed quantum dots, J. Phys. Chem. B, 2006, 110, 9034-9040.
Jifang Weng, Jicun Ren*, Luminescent Quantum Dots: An Attractive Promising Tool in Biomedicine, Current Medicinal Chemistry, 2006, 13, 897-909.
Huifeng Qian, Jicun Ren*, Facile one-pot synthesis of highly luminescent, water-soluble and bio-compatible glutathione coated CdTe quantum Dots in aqueous phase, Small, 2006, 2,747-751.
Xiangyi Huang, Jicun Ren*, Chemiluminescence detection in capillary electrophoresis and microchip capillary electrophoresis, TRAC:Trends in Analytical Chemistry, 2006, 25,155-156.
Chaoqing Dong, Rui Bi, Huifeng Qian, Jicun Ren* Coupling fluorescence correlation Spectroscopy with Microchip Electrophoresis to Determine Effective Surface Charge of Water-Soluble QDs, Small, 2006, 2,534-538.
Liang Li, Huifeng Qian, Jicun Ren*,CdTe@Co(OH)(core/shell) nanoparticles: aqueous synthesis and characterizations,Chemical Communication,2005, 4083-4085.
Liang Li, Huifeng Qian, Jicun Ren*, Rapid Synthesis of Highly Luminescent CdTe Nanocrystals in Aqueous Phase by Microwave Irradiation with Controllable Temperature, Chemical Communication, 2005, 528-530.
Jicun Ren*, Arve Ulvik, Helga Refsum, Per Magne Ueland , Uracil in Human DNA from Subjects with Normal and Impaired Folate Status, as Determined by High Performance Liquid Chromatography-Tandem Mass, Analytical Chemistry, 2002, 74, 295-299.
Jicun Ren*, Xiangyi Huang, Highly Sensitive and Universal Indirect Chemiluminescence Detection for Capillary Electrophoresis of Cations Using Cobalt(II) As A Novel Probe Ion,Analytical Chemistry, 2001, 73, 2663-2668.
出版专着
Jicun Ren, 《Capillary Electrophoresis of Nucleic Acid》, Chapter 10 and Chapter 19, Jan., 2001, Humana Press Inc., Totowa, NJ, USA.